Listy Biometryczne - Biometrical Letters vol. 42(2), 2005, pp. 156-16


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BAYESIAN DETECTION OF SINGLE GENE DETERMINING QUANTITATIVE TRAIT BY THRESHOLD MODEL

Anita Dobek1, Tomasz Szwaczkowski2, Krzysztof Moliński1, Ewa Skotarczak1

1Department of Mathematical and Statistical Methods,
2Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University
of Poznań, Poland


A method for the identification of single genes determining quantitative traits is given. The starting point is the analysis of a threshold model with one threshold of an unobservable variable values, the variable which determines the phenotype of an individual. The values of this variable depend, beside the single gene, on fixed effects, polygenic effects and in the case of repeated measurements of these traits also permanent environmental effects.


Gibbs sampling, quantitative trait, single genes, threshold model.